Pesquisa sobre: DEAD BOX PROTEIN 58 
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Descritor Inglês:   DEAD Box Protein 58 
Descritor Espanhol:   Proteína 58 DEAD Box 
Descritor Português:   Proteína DEAD-box 58 
Sinônimos Inglês:   DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58
Probable ATP-Dependent RNA Helicase DDX58
RIG-I-like Receptor 1
Probable ATP Dependent RNA Helicase DDX58
RIG I like Receptor 1  
Categoria:   D08.811.913.696.445.735.720.249.750
Definição Inglês:   A DEAD-box RNA helicase that contains an N-terminal DEATH-LIKE DOMAIN, AAA+ ATPase domain, and C-terminal RNA HELICASE activity. It functions as an innate immune receptor through its recognition of viral nucleic acids. It also induces the expression of INTERFERON TYPE I and proinflammatory CYTOKINES. Its ligands include: 5'-triphosphorylated SINGLE-STRANDED RNA, DOUBLE-STRANDED RNA (dsRNA), and short dsRNA (less than 1 kb in length). 
Nota Histórica Inglês:   2017 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   56506 
Identificador Único:   D000071457 

Ocorrência na BVS:
 

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